I have a stomachache. Is it a stomach ulcer?

Is the incidence of peptic ulcer related to gastric acid? The increase of gastric acid is not the only mechanism of peptic ulcer. Gastric acid is one of the important factors in the occurrence of peptic ulcer. About 90% of duodenal ulcer and 80% of gastric ulcer are caused by Helicobacter pylori (Hp) infection. Is the incidence of peptic ulcer related to the season? the incidence of some patients with peptic ulcer has a certain seasonality, which is more harmful to patients with active ulcer and patients with a history of ulcer, and can often aggravate ulcer, bleed or recur. Epidemiology has not confirmed that drinks such as coffee and strong tea are associated with the occurrence of peptic ulcer, but long-term consumption may increase the risk of peptic ulcer. Is peptic ulcer hereditary? genetic factors may be one of the causes of peptic ulcer. There is a phenomenon of family aggregation in the pathogenesis of peptic ulcer. Who is susceptible to peptic ulcer? 3. People with family history of peptic ulcer.

Many people have a stomachache, always suspect that they have gastric ulcers, and even worry that long-term gastric ulcers will lead to cancer, but they are not willing to carry out endoscopic examination, thinking that endoscopic examination is too uncomfortable. In fact, the medical so-called gastric ulcer is only one kind of ulcer, the following knowledge can give us a correct understanding of peptic ulcer.

What is peptic ulcer?

Peptic ulcer refers to the inflammatory reaction and necrotic lesions of the mucosa under the action of various pathogenic factors, which can reach the muscular layer of the mucosa.Among them, stomach and duodenum are the most common, so they are also called gastric and duodenal ulcers.

Is the incidence of peptic ulcer related to gastric acid?

Gastric acid plays a key role in the formation of ulcers, that is, "no ulcer without acid".

The increase of gastric acid is not the only mechanism of peptic ulcer, but a certain level of gastric acid is a necessary condition for the occurrence of most peptic ulcer.People whose maximum gastric acid output is less than 12-15 mmol/h rarely develop duodenal ulcer.

H2 receptor antagonists (tidine), proton pump inhibitors (prazoles) and antacids can promote the healing of gastric and duodenal ulcers. Therefore, gastric acid is one of the important factors in the occurrence of peptic ulcer.

Is peptic ulcer related to Helicobacter pylori?

Clinical data show thatAbout 90% of duodenal ulcers and 80% of gastric ulcers are caused by Helicobacter pylori (Hp) infection.Hp destroys the gastric mucosal barrier ("roof"), resulting in reverse diffusion of hydrogen ions ("rain leakage") to the gastric mucosa, that is, the "house leakage theory". Eradicating Hp and repairing the "roof" can significantly reduce the recurrence rate of gastric ulcers.

Helicobacter pylori (Hp) infection is a worldwide problem, and the infection rate increases with age.

1. China is a country with high infection rate, and the infection rate of natural population is40% 60%

The detection rate of 2.Hp in patients with chronic gastritis was60% 70%

3. Gastric ulcer is70% / 80%

4. In the gastric antrum of patients with duodenal ulcer80% / 100%.

The transmission of the bacteria is mainly through oral-fecal or oral-to-oral transmission from person to person. However, only 15% of people infected with HP have peptic ulcer, indicating that in addition to bacterial ability, genetic susceptibility and eating habits also play a role.

Is the incidence of peptic ulcer related to the season?

The incidence of some patients with peptic ulcer has a certain seasonality, regardless of initial or recurrent.The disease occurs when the temperature is changeable in late autumn or early spring.However, the incidence in summer is low, and the specific reason for this seasonal difference is not clear.

What are the effects of tobacco, alcohol and tea on people with peptic ulcer?

Smokers are more likely to develop peptic ulcer than non-smokers, and drinking alcohol has obvious damaging effect on gastric mucosa.It will cause gastritis and promote the formation of ulcers, which is more harmful to patients with active ulcers and patients with a history of ulcers, and can often aggravate ulcers, bleed or recur.

Coffee, strong tea and other drinks can significantly stimulate gastric acid secretion, epidemiology has not confirmed that coffee, strong tea and other drinks are related to the occurrence of peptic ulcer. ButLong-term consumption may increase the risk of peptic ulcer.

Is peptic ulcer hereditary?

Genetic factors may be one of the causes of peptic ulcer, and there is family aggregation in the pathogenesis of peptic ulcer.

Is peptic ulcer related to blood type?

Type O bloodAmong the population, the incidence of duodenal ulcer was higher than that of other blood types.35% higherLeft and right.

Who is susceptible to peptic ulcer?

1.Hp infected person

two。 Long-term heavy use of NSAIDs, such as aspirin, anticoagulants, adrenocortical hormones, antihypertensive drugs

3. People with family history of peptic ulcer

4. Long-term smokers, overeaters and irregular eaters

5. People with high mental stress, anxiety and depression

6. Some chronic diseases, such as liver cirrhosis, chronic obstructive pulmonary disease, rheumatoid arthritis, uremia, primary hyperparathyroidism and gastrinoma are prone to ulcers.

The above people are prone to peptic ulcer, the incidence of male is higher than that of female, and the young are more than the old.

How to distinguish gastric ulcer and duodenal ulcer?

1. The location of gastric ulcer and duodenal ulcer is different.

1. A chronic ulcer that occurs in the stomach as its name implies, including the antrum, angle, body, and fundus.
2. Duodenal ulcer is a chronic ulcer that occurs in the duodenum, including the bulb and the descending part.

two。 Different clinical manifestations of gastric ulcer and duodenal ulcer

3. A small number of gastric ulcers can become cancerous.Duodenal ulcers generally do not become cancerous.

Can peptic ulcer become cancerous?

Canceration of gastric ulcer is still a controversial issue. It is generally estimated that the incidence of canceration of gastric ulcer is but2% to 5%But duodenal bulb ulcers generally do not cause canceration Recurrent gastric ulcer has been considered by many experts as a precancerous lesion.

Who should be on guard against canceration of gastric ulcer?

All middle-aged and above patients with gastric ulcers should suspect the possibility of canceration of gastric ulcers under the following conditions:

1. Strict medical treatment for 4 to 6 weeks, no improvement in symptoms or no complications, loss of rhythm of pain, loss of appetite and significant weight loss.

two。 Those with persistent positive fecal occult blood test and anemia

3. X-ray barium meal or gastroscopy can not exclude the malignant transformation of gastric ulcer.

4. Ulcer diameter is larger than 1cm, and lingering does not heal, the age of ≥ is 40 years old.

5. Recent symptoms are repeated, such as hiccups, belching, abdominal pain, and accompanied by weight loss.

6. More than 5 years after gastric operation, there were unexplained upper abdominal distension, belching, discomfort, fatigue, emaciation and so on.

All the above people must be examined by gastroscopy regularly. Especially forLong-term history of chronic gastric ulcer, age over 45 years old, stubborn ulcerWe should be vigilant, take multiple biopsies under gastroscope for pathological examination, and recheck gastroscope after active treatment until the ulcer is completely healed, and follow-up regularly if necessary.